The preterm labor associated ADAMTS2 gene is induced by glucocorticoids
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چکیده
منابع مشابه
Notch Signaling in Inflammation-Induced Preterm Labor
Notch signaling plays an important role in regulation of innate immune responses and trophoblast function during pregnancy. To identify the role of Notch signaling in preterm labor, Notch receptors (Notch1-4), its ligands (DLL (Delta-like protein)-1/3/4), Jagged 1/2) and Notch-induced transcription factor Hes1 were assessed during preterm labor. Preterm labor was initiated on gestation day 14.5...
متن کاملMaternal glucocorticoids increase endotoxin-induced lung inflammation in preterm lambs.
Antenatal betamethasone (Beta) is widely used in women with asymptomatic chorioamnionitis at risk for preterm delivery, but its effects on fetal inflammation are unstudied. Groups of ewes at 109 +/- 1 days of gestation received the following treatments: intra-amniotic (IA) saline (control), 0.5 mg/kg intramuscular Beta, 10 mg IA endotoxin (Endo), and Beta + 2 h later Endo (Beta + Endo). Beta su...
متن کاملAnaphylaxis induced by glucocorticoids.
Glucocorticoids are frequently used to treat allergic reactions. Therefore, allergic reactions to systemic glucocorticoids in particular are considered most unlikely and are not well known. We report on a 23-year-old woman with atopic dermatitis who had an anaphylactic reaction after oral administration of prednisolone. On treatment with epinephrine, antihistamines and volume symptoms resolved....
متن کاملThe common vaginal commensal bacterium Ureaplasma parvum is associated with chorioamnionitis in extreme preterm labor.
OBJECTIVE To assess the association of vaginal commensal and low-grade pathogenic bacteria including Ureaplasma parvum, Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, Group B streptococcus (GBS), and Gardnerella vaginalis, in women who delivered preterm at less than 37-week gestation in the presence or absence of inflammation of the chorioamnionitic membranes. METHODS A ca...
متن کاملThe Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor
Background Preterm birth with a prevalence of about 10% causes 75-95% of prenatal mortality, and one of the effective factors of it is hormonal factors. This study aimed to investigate the effect of oral medroxy progesterone on reducing preterm labor in women with a history of preterm labor. Materials and Methods This double-...
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ژورنال
عنوان ژورنال: American Journal of Obstetrics and Gynecology
سال: 2018
ISSN: 0002-9378
DOI: 10.1016/j.ajog.2018.03.024